Structural Characteristics

Cryptand 222 has a three-dimensional cage structure, with the N₂O₆ moiety in the molecule being used for coordination. Its cage structure, composed of two nitrogen atoms and six oxygen atoms, can form stable complexes with metal ions.

Main Applications

Metal Ion Chelator:

In solution, cryptand 222 is commonly used as a metal ion chelator, capable of complexing with alkali metal cations, such as in the preparation of K⁺-imprinted nanoparticles.

Electrolyte Additive:

It can be used as an electrolyte additive for isotachophoresis, particularly suitable for the separation of small molecule ions and for alkali metal cation analysis.

Structure-Directing Agent:

In materials science, it can be used as a structure-directing agent in the preparation of LTA-type AlPO₄ crystals.

Drug Carrier:

Due to its excellent biocompatibility, it can be used as a drug carrier to precisely deliver drugs to the site of disease, improving drug efficacy and reducing side effects.

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